Cancer [electronic resource] /
With contributions by numerous experts
edited by Robert H. Bradbury.
- XIV, 452 p. 32 illus., 4 illus. in color. online resource.
- Topics in Medicinal Chemistry, 1 1862-2461 ; .
- Topics in Medicinal Chemistry, 1 .
Overview -- Anti-hormone Therapy: Principles of Endocrine Therapy of Cancer -- Inhibition of Growth Factor Signaling by Small-Molecule Inhibitors of ErbB, Raf, and MEK -- Farnesyl Protein Transferase Inhibitors: Medicinal Chemistry, Molecular Mechanisms, and Progress in the Clinic -- Survival Signaling -- Progress in the Development of Agents to Control the Cell Cycle -- HDAC Inhibition in Cancer Therapy: An Increasingly Intriguing Tale of Chemistry, Biology and Clinical Benefit -- Development of Angiogenesis Inhibitors to Vascular Endothelial Growth Factor Receptor 2 for Cancer Therapy -- Novel Small-Molecule Inhibitors of Src Kinase for Cancer Therapy -- Bcr-Abl Kinase Inhibitors.