TY - BOOK AU - ED - SpringerLink (Online service) TI - Hydrogenosomes and Mitosomes: Mitochondria of Anaerobic Eukaryotes T2 - Microbiology Monographs, SN - 9783540767336 AV - QR1-502 U1 - 579 23 PY - 2008/// CY - Berlin, Heidelberg PB - Springer Berlin Heidelberg KW - Life sciences KW - Biochemistry KW - Cytology KW - Evolution (Biology) KW - Microbiology KW - Life Sciences KW - Eukaryotic Microbiology KW - Cell Biology KW - Biochemistry, general KW - Evolutionary Biology N1 - Anaerobic Eukaryotes in Pursuit of Phylogenetic Normality: the Evolution of Hydrogenosomes and Mitosomes -- Protein Import into Hydrogenosomes and Mitosomes -- Structure of the Hydrogenosome -- Hydrogenosomes of Anaerobic Ciliates -- Metabolism of Trichomonad Hydrogenosomes -- Hydrogenosomes of Anaerobic Chytrids: An Alternative Way to Adapt to Anaerobic Environments -- The Proteome of T.vaginalis Hydrogenosomes -- Hydrogenosome: The Site of 5-Nitroimidazole Activation and Resistance -- Mitosomes in Parasitic Protists -- The Mitochondrion-Related Organelle of Cryptosporidium parvum -- Mitochondrial Remnant in Blastocystis -- Possible Mitochondria-Related Organelles in Poorly-Studied ǣAmitochondriateǥ Eukaryotes; ZDB-2-SBL N2 - "Hydrogenosomes and Mitosomes: Mitochondria of Anaerobic Eukaryotes" provides a summary of the current knowledge of these organelles, which occur in unicellular, often parasitic organisms, including human pathogens. The distribution of these organelles is broad, but they were detected primarily in an anoxic habitat or nutrient rich intracellular niche that permits life without the efficient energy generating system of typical mitochondria. Their common characteristic is that they lack the aerobic energy conservation system of typical mitochondria and that they are usually the site of the synthesis of iron-sulfur clusters, regarded as the only indispensable function of eukaryotic mitochondria. These mitochondria-related organelles exhibit a variety of structures and functions. This work describes properties such as protein import, structure, metabolism, adaptation, proteome and their role in drug activation and resistance. Further topics include the evolution and biogenesis of these organelles UR - http://dx.doi.org/10.1007/978-3-540-76733-6 ER -