TY  - BOOK
AU  - 
ED  - SpringerLink (Online service)
TI  - Sex and Gender Differences in Pharmacology
T2  - Handbook of Experimental Pharmacology,
SN  - 9783642307263
AV  - RM1-950 
U1  - 615 23
PY  - 2012///
CY  - Berlin, Heidelberg
PB  - Springer Berlin Heidelberg, Imprint: Springer
KW  - Medicine
KW  - Toxicology
KW  - Pharmaceutical technology
KW  - Biomedicine
KW  - Pharmacology/Toxicology
KW  - Molecular Medicine
KW  - Pharmaceutical Sciences/Technology
N1  - From the contents -- Preface -- Part 1: Sex differences in mechanisms of disease -- Part 2:Sex differences in pharmacoákinetics, in drug development and use -- Part 3: Sex differences in different therapeutic areas; ZDB-2-SBL
N2  - This is the very first book to deal with sex and gender differences in drug therapy - an increasingly recognized medical need. It starts with an overview on S/G in clinical syndromes and a documentation of the medical and socioeconomic damage caused by gender specific adverse drug effects. Part I covers S/G differences in pharmacokinetics. Researchers will be satisfied by the detailed discussion of the mechanisms of S/G differences in drug effects that represents cutting edge science and includes interaction of drugs with sex hormones, genomic and epigenetic mechanisms. It also covers S/G in drug development, in animal models and clinical development and S/G in drug prescriptions. Part II targets S/G differences in drug effects in cardiovascular, pulmonary, CNS, neuromuscular, neuropsychiatric and metabolic diseases, in cancer, inflammation, and rheumatic diseases, in bacterial and retroviral infections, thrombosis, embolism. New drugs will be discussed
UR  - http://dx.doi.org/10.1007/978-3-642-30726-3
ER  -