000 03871nam a22005655i 4500
003 DE-He213
005 20191014003907.0
007 cr nn 008mamaa
008 100301s2010 gw | s |||| 0|eng d
020 6 4 _a9783642054204
_9978-3-642-05420-4
024 8 7 _a10.1007/978-3-642-05420-4
_2doi
050 8 4 _aR856-857
072 8 7 _aMQW
_2bicssc
072 8 7 _aTEC009000
_2bisacsh
082 _a610.28
_223
100 8 1 _aRubinsky, Boris.
_eeditor.
_9157933
245 9 7 _aIrreversible Electroporation
_h[electronic resource] /
_cedited by Boris Rubinsky.
001 000067359
300 6 4 _aXIV, 313 p.
_bonline resource.
490 8 1 _aSeries in Biomedical Engineering,
_x1864-5763
505 8 0 _aHistorical Review of Irreversible Electroporation in Medicine -- Tissue Electroporation as a Bioelectric Phenomenon: Basic Concepts -- Experimental Studies on Irreversible Electroporation of Cells -- Mechanism of Irreversible Electroporation in Cells: Insight from the Models -- Thermal Aspects of Irreversible Electroporation -- Experimental Studies on Non-thermal Irreversible Electroporation in Tissue -- Finite Element Modeling of in Vivo Electroporation -- Optimization and Numerical Modeling in Irreversible Electroporation Treatment Planning -- The Place of the Electroporation-Based Antitumor Therapies in the Electrical Armamentarium against Cancer -- Irreversible Electroporation: First Patient Experience Focal Therapy of Prostate Cancer -- Human Experience with Irreversible Electroporation -- Irreversible Electroporation Systems for Clinical Use -- The Use of Irreversible Electroporation in Food Preservation.
520 6 4 _aThis is an brief introduction to the emerging field of irreversible electroporation in medicine. Certain electrical fields when applied across a cell can have as a sole effect the permeabilization of the cell membrane, presumable through the formation of nanoscale defects in the cell membrane. Sometimes this process leads to cell death, primarily when the electrical fields cause permanent permeabilization of the membrane and the consequent loss of cell homeostasis, in a process known as irreversible electroporation. This is an unusual mode of cell death that is not fully understood yet. While the phenomenon of irreversible electroporation may have been known for centuries it has become only recently rigorously considered in medicine for various applications of tissue ablation. A brief historical perspective of irreversible electroporation is presentedfollowed by general reviews on the theory and experiment fundamentals and by reports on the most recent theoretical, experimental and clinical studies.
650 8 0 _aEngineering.
_9157934
650 8 0 _aOncology.
_99111
650 8 0 _aCytology.
_910299
650 8 0 _aElectrophoresis.
_966622
650 8 0 _aPhysiology
_xMathematics.
_911711
650 8 0 _aMicrowaves.
_99379
650 8 0 _aBiomedical engineering.
_9157935
650 _aEngineering.
_9157934
650 _aBiomedical Engineering.
_9157936
650 _aElectrophoresis.
_966622
650 _aOncology.
_99111
650 _aCell Biology.
_910306
650 _aPhysiological, Cellular and Medical Topics.
_911712
650 _aMicrowaves, RF and Optical Engineering.
_99383
710 8 2 _aSpringerLink (Online service)
_9157937
773 8 0 _tSpringer eBooks
776 _iPrinted edition:
_z9783642054198
830 8 0 _aSeries in Biomedical Engineering,
_x1864-5763
_9157938
856 _uhttp://dx.doi.org/10.1007/978-3-642-05420-4
_zde clik aquí para ver el libro electrónico
264 8 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2010.
336 6 4 _atext
_btxt
_2rdacontent
337 6 4 _acomputer
_bc
_2rdamedia
338 6 4 _aonline resource
_bcr
_2rdacarrier
347 6 4 _atext file
_bPDF
_2rda
516 6 4 _aZDB-2-ENG
999 _c67089
_d67089
942 _c05