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| 008 | 110117s2011 gw | s |||| 0|eng d | ||
| 020 | 6 | 4 |
_a9783642170836 _9978-3-642-17083-6 |
| 024 | 8 | 7 |
_a10.1007/978-3-642-17083-6 _2doi |
| 050 | 8 | 4 | _aR-RZ |
| 072 | 8 | 7 |
_aMBGR _2bicssc |
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_aMED000000 _2bisacsh |
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_a610 _223 |
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| 100 | 8 | 1 |
_aVassilev, Lyubomir. _eeditor. _9171748 |
| 245 | 9 | 7 |
_aSmall-Molecule Inhibitors of Protein-Protein Interactions _h[electronic resource] / _cedited by Lyubomir Vassilev, David Fry. |
| 001 | 000069193 | ||
| 300 | 6 | 4 |
_aX, 174 p. _bonline resource. |
| 490 | 8 | 1 |
_aCurrent Topics in Microbiology and Immunology, _x0070-217X ; _v348 |
| 505 | 8 | 0 | _aPreface -- Hydrogen-bonded synthetic mimics of protein secondary structure as disruptors of protein-protein interactions -- Small-molecule inhibitors of IL-2/IL-2R: lessons learned and applied -- Small Molecule Inhibitors of the Human Papillomavirus E1-E2 Interaction -- Design of small-molecule Smac mimetics as IAP antagonists -- Small-molecule inhibitors reveal a new function for Bcl-2 as a pro-angiogenic signaling molecule -- Small-molecule modulators of c-Myc/Max and Max/Max interactions.- Small-molecule inhibitors of the p53-MDM2 interaction -- Subject index. |
| 520 | 6 | 4 | _abody> In this volume, the editors have collected the knowledgeable insights of a number of leaders in this field - researchers who have achieved success in addressing the difficult problem of inhibiting protein-protein interactions. These researchers describe their unique approaches, and share experiences, results, thoughts, and opinions. The content of the articles is rich, and in terms of scope ranges from generalized approaches to specific case studies. There are various focal points, including methodologies and the molecules themselves. Ultimately, there are numerous lessons to be taken away from this collection, and the editors hope that this snapshot of the current state of the art in developing protein-protein inhibitors not only pays tribute to the past successes, but also generates excitement about the future potential of this field. |
| 650 | 8 | 0 |
_aMedicine. _94382 |
| 650 |
_aBiomedicine. _94386 |
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| 650 |
_aBiomedicine general. _99415 |
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| 700 | 8 | 1 |
_aFry, David. _eeditor. _9171749 |
| 710 | 8 | 2 |
_aSpringerLink (Online service) _9171750 |
| 773 | 8 | 0 | _tSpringer eBooks |
| 776 |
_iPrinted edition: _z9783642170829 |
||
| 830 | 8 | 0 |
_aCurrent Topics in Microbiology and Immunology, _x0070-217X ; _v348 _9171751 |
| 856 |
_uhttp://dx.doi.org/10.1007/978-3-642-17083-6 _zde clik aquí para ver el libro electrónico |
||
| 264 | 8 | 1 |
_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg, _c2011. |
| 336 | 6 | 4 |
_atext _btxt _2rdacontent |
| 337 | 6 | 4 |
_acomputer _bc _2rdamedia |
| 338 | 6 | 4 |
_aonline resource _bcr _2rdacarrier |
| 347 | 6 | 4 |
_atext file _bPDF _2rda |
| 516 | 6 | 4 | _aZDB-2-SBL |
| 999 |
_c68923 _d68923 |
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