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008 | 120707s2012 gw | s |||| 0|eng d | ||
020 | 6 | 4 |
_a9783642305177 _9978-3-642-30517-7 |
024 | 8 | 7 |
_a10.1007/978-3-642-30517-7 _2doi |
050 | 8 | 4 | _aQH505 |
072 | 8 | 7 |
_aPHVN _2bicssc |
072 | 8 | 7 |
_aPHVD _2bicssc |
072 | 8 | 7 |
_aSCI009000 _2bisacsh |
082 |
_a571.4 _223 |
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100 | 8 | 1 |
_aOuldridge, Thomas E. _eauthor. _9194153 |
245 | 9 | 7 |
_aCoarse-Grained Modelling of DNA and DNA Self-Assembly _h[electronic resource] / _cby Thomas E. Ouldridge. |
001 | 000072292 | ||
300 | 6 | 4 |
_aXII, 176 p. _bonline resource. |
490 | 8 | 1 |
_aSpringer Theses, Recognizing Outstanding Ph.D. Research, _x2190-5053 |
505 | 8 | 0 | _aA Novel DNA Model -- Methods -- Finite Size Effects -- Structural and Mechanical Properties of Model DNA -- Thermodynamic Properties of Model DNA -- Modelling DNA Tweezers -- Modelling a DNA Walker. |
520 | 6 | 4 | _aThis thesis presents a novel coarse-grained model of DNA, in which bases are represented as rigid nucleotides. The model is shown to quantitatively reproduce many phenomena, including elastic properties of the double-stranded state, hairpin formation in single strands and hybridization of pairs of strands to form duplexes, the first time such a wide range of properties has been captured by a coarse-grained model. The scope and potential of the model is demonstrated by simulating DNA tweezers, an iconic nanodevice, and a two-footed DNA walker the first time that coarse-grained modelling has been applied to dynamic DNA nanotechnology. |
650 | 8 | 0 |
_aPhysics. _9194154 |
650 | 8 | 0 |
_aPolymers. _913475 |
650 | 8 | 0 |
_aNanotechnology. _99777 |
650 |
_aPhysics. _9194154 |
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650 |
_aBiophysics and Biological Physics. _99136 |
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650 |
_aNanotechnology. _99777 |
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650 |
_aPolymer Sciences. _913477 |
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650 |
_aStatistical Physics, Dynamical Systems and Complexity. _912503 |
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650 |
_aSoft and Granular Matter, Complex Fluids and Microfluidics. _912853 |
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710 | 8 | 2 |
_aSpringerLink (Online service) _9194155 |
773 | 8 | 0 | _tSpringer eBooks |
776 |
_iPrinted edition: _z9783642305160 |
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830 | 8 | 0 |
_aSpringer Theses, Recognizing Outstanding Ph.D. Research, _x2190-5053 _9194156 |
856 |
_uhttp://dx.doi.org/10.1007/978-3-642-30517-7 _zde clik aquí para ver el libro electrónico |
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264 | 8 | 1 |
_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg : _bImprint: Springer, _c2012. |
336 | 6 | 4 |
_atext _btxt _2rdacontent |
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_acomputer _bc _2rdamedia |
338 | 6 | 4 |
_aonline resource _bcr _2rdacarrier |
347 | 6 | 4 |
_atext file _bPDF _2rda |
516 | 6 | 4 | _aZDB-2-PHA |
999 |
_c72022 _d72022 |
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