000 04027nam a22005055i 4500
003 DE-He213
005 20191014063943.0
007 cr nn 008mamaa
008 120705s2012 ne | s |||| 0|eng d
020 6 4 _a9789400712263
_9978-94-007-1226-3
024 8 7 _a10.1007/978-94-007-1226-3
_2doi
050 8 4 _aQH505
072 8 7 _aPHVN
_2bicssc
072 8 7 _aPHVD
_2bicssc
072 8 7 _aSCI009000
_2bisacsh
082 _a571.4
_223
100 8 1 _aSpoto, Giuseppe.
_eeditor.
_9233331
245 9 7 _aDetection of Non-Amplified Genomic DNA
_h[electronic resource] /
_cedited by Giuseppe Spoto, Roberto Corradini.
001 000078628
300 6 4 _aXIV, 318 p.
_bonline resource.
490 8 1 _aSoft and Biological Matter,
_x2213-1736
505 8 0 _aPreface -- List of contributors -- PartI DNA analysis: current issues -- 1 Genetic analyses in health laboratories: current status and expectations -- 2 DNA analyses in food safety and quality: current status and expectations -- Part II Advanced materials forultrasensitiveanalysis -- 3 Engineered nanostructures forultrasensitive DNA detection -- 4 Advanced molecularprobes for sequence-specificDNA recognition -- 5 Charged conjugated polymers -- 6 Optical detection of non-amplified genomic DNA -- 7 Electrochemical detection of DNA using nanomaterials-based sensors -- 8 Piezoelectric sensing for sensitive detection of DNA -- 9 Surface plasmon resonance-based methods -- 10 Parallel optical and electrochemical DNA detection -- 11 Recent advances in DNA sequencing technologies -- Subject Index.
520 6 4 _aThis book offers a state-of-the-art overview on non amplified DNA detection methods and provides chemists, biochemists, biotechnologists and material scientists with an introduction to these methods. In fact all these fields have dedicated resources to the problem of nucleic acid detection, each contributing with their own specific methods and concepts. This book will explain the basic principles of the different non amplified DNA detection methods available, highlighting their respective advantages and limitations. The importance of non-amplified DNA sequencing technologies will be also discussed. Non-amplified DNA detection can be achieved by adopting different techniques. Such techniques have allowed the commercialization of innovative platforms for DNA detection that are expected to break into the DNA diagnostics market. The enhanced sensitivity required for the detection of non amplified genomic DNA has prompted new strategies that can achieve ultrasensitivity by combining specific materials with specific detection tools. Advanced materials play multiple roles in ultrasensitive detection. Optical and electrochemical detection tools are among the most widely investigated to analyze non amplified nucleic acids. Biosensors based on piezoelectric crystal have been also used to detect unamplified genomic DNA. The main scientific topics related to DNA diagnostics are discussed by an outstanding set of authors with proven experience in the field.
650 8 0 _aPhysics.
_9233332
650 8 0 _aAnalytical biochemistry.
_99155
650 8 0 _aBiomedical engineering.
_9233333
650 _aPhysics.
_9233332
650 _aBiophysics and Biological Physics.
_99136
650 _aAnalytical Chemistry.
_99158
650 _aBiomedical Engineering.
_9233334
700 8 1 _aCorradini, Roberto.
_eeditor.
_9233335
710 8 2 _aSpringerLink (Online service)
_9233336
773 8 0 _tSpringer eBooks
776 _iPrinted edition:
_z9789400712256
830 8 0 _aSoft and Biological Matter,
_x2213-1736
_9233337
856 _uhttp://dx.doi.org/10.1007/978-94-007-1226-3
_zde clik aquí para ver el libro electrónico
264 8 1 _aDordrecht :
_bSpringer Netherlands :
_bImprint: Springer,
_c2012.
336 6 4 _atext
_btxt
_2rdacontent
337 6 4 _acomputer
_bc
_2rdamedia
338 6 4 _aonline resource
_bcr
_2rdacarrier
347 6 4 _atext file
_bPDF
_2rda
912 6 4 _aZDB-2-PHA
999 _c78358
_d78358
942 _c05